Literature Review Matrix of Articles Used in Critical Appraisal

Literature Review Matrix of Articles Used in Critical Appraisal
Table 1
Literature Review Matrix of Articles Used in Critical Appraisal

Study Citation and Level of Evidence
Purpose
Design
Sample
Measurement tool(s)/Instrument(s)
Statistical Analysis
Key Findings

Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).
Level II
Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months.
Single-center parallel group randomized double-blind placebo controlled trial
84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.
Azithromycin therapy group (n=42) and placebo group (n=42)
Leicester Cough Questionnaire (LCQ)
St. George’s Respiratory Questionnaire (SGRQ)
Short Form 36 (SF-36)
Literature Review Matrix of Articles Used in Critical Appraisal
 
 
Intention-to-treat analysis.
Log-rank test.
Kaplan-Meier curves.
Chi-square tests.
ANCOVA analysis.
LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group.

Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.
Level III
Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression
Quasi-experimental pretest-postest control group
48 adults > 65 years with mild cognitive impairment (MCI)
Intervention group (n=24); Control group (n=24)
Serum homocysteine levels
Geriatric Depression Scale Short Form Korean Version (GDSSF-K)
Mini Mental State Examination-Korean (MMSE-K)
 
Two group t test
Chi-square test for association
Fisher’s exact test
Intervention group had significantly increased cognitive function  compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group

 
 
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Table 1
Literature Review Matrix of Articles Used in Critical Appraisal

Study Citation and Level of Evidence
Purpose
Design
Sample
Measurement tool(s)/Instrument(s)
Statistical Analysis
Key Findings

Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).
Level II
Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months.
Single-center parallel group randomized double-blind placebo controlled trial
84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.
Azithromycin therapy group (n=42) and placebo group (n=42)
Leicester Cough Questionnaire (LCQ)
St. George’s Respiratory Questionnaire (SGRQ)
Short Form 36 (SF-36)
 
 
Intention-to-treat analysis.
Log-rank test.
Kaplan-Meier curves.
Chi-square tests.
ANCOVA analysis.
LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group.

Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.
Level III
Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression
Quasi-experimental pretest-postest control group
Literature Review Matrix of Articles Used in Critical Appraisal
48 adults > 65 years with mild cognitive impairment (MCI)
Intervention group (n=24); Control group (n=24)
Serum homocysteine levels
Geriatric Depression Scale Short Form Korean Version (GDSSF-K)
Mini Mental State Examination-Korean (MMSE-K)
 
Two group t test
Chi-square test for association
Fisher’s exact test
Literature Review Matrix of Articles Used in Critical Appraisal
Intervention group had significantly increased cognitive function  compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group

 

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