NUR 315 Discussion Cellular Adaptation

NUR 315 Discussion Cellular Adaptation
Discussion: Cellular Adaptation

Explain at least two types of cellular damage that are largely responsible for progression from reversible to irreversible cellular injury.
In your responses to peers, discuss the most common type of cellular injury occurring within the human body.
To complete this assignment, review the Discussion Rubric document. NUR 315 Discussion Cellular Adaptation
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Cellular injury “leads to injury of tissues and organs ultimately determining the structural patterns of disease” according to McCance and Huether (2019, p.49). Injury can be caused by numerous things including hypoxia, toxicity, immune reactions, or even genetics. When a cell is injured it can either recover, which would be reversible injury, or it can die which is irreversible injury (McCance and Huether).

An example cellular injury that can start as reversible but ultimately lead to irreversible damage is, of course, hypoxia. McCance and Huether explain hypoxia as the lack of oxygen needed for the cell and is the most common form of cellular injury caused by many things including decreased hemoglobin, respiratory disease, or simply lack of oxygen in the air. For example, a patient experiencing a NSTEMI in in the stage where cellular injury can be reversible. There is still a blockage to some extent, which intermittently causes ischemia to the cells, but hasn’t yet evolved into a full-blown heart attack. A STEMI has now progressed to a fully blocked artery causing death to cells as they have no blood flow. NUR 315 Discussion Cellular Adaptation. If left to long untreated to much heart muscle may become permanently ischemic resulting in cell death and ultimately patient death. It only takes 1 minute of interrupted flow to the heart for it to weaken and become less efficient and 3-5 minutes for the affected area of the heart to no longer work (McCance and Huether). NUR 315 Discussion Cellular Adaptation.
Another example of cellular injury that can lead to irreversible damage is caused by chemicals. Being from NH where we have cold winters I was intrigued by McCance and Huether’s section regarding indoor air pollution from solid fuels like wood for open fires. If homes aren’t well ventilated it can cause an increased risk for particles and carbon monoxide poisoning. According to McCance and Huether, “several studies have found that long-term particulate matter air pollution exposure is associated with cardiovascular disease (CVD) morbidity and mortality (p61). It would make sense that repeat exposure to harsh chemicals eventually cause cell damage and then death as exposure continues. NUR 315 Discussion Cellular Adaptation.
Discussion: Cellular Adaptation Reference
McCance, K. L., & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in     adults and children (8th Ed.). St. Louis, MO: Elsevier.
Discussion Rubric: Undergraduate: Discussion: Cellular Adaptation

Your active participation in the discussion forums is essential to your overall success this term. Discussion questions are designed to help you make meaningful connections between the course content and the larger concepts and goals of the course. These discussions offer you the opportunity to express your own thoughts, ask questions for clarification, and gain insight from your classmates’ responses and instructor’s guidance.
Requirements for Discussion Board Assignments
Students are required to post one initial post and to follow up with at least two response posts for each discussion board assignment. NUR 315 Discussion Cellular Adaptation.
For your initial post (1), you must do the following:
• Compose a post of one to two paragraphs.
• In Module One, complete the initial post by Thursday at 11:59 p.m. Eastern Time.
• In Modules Two through Eight, complete the initial post by Thursday at 11:59 p.m. of your local time zone.
• Take into consideration material such as course content and other discussion boards from the current module and previous modules, when appropriate (make sure you are using proper citation methods for your discipline when referencing scholarly or popular resources). NUR 315 Discussion Cellular Adaptation.
For your response posts (2), you must do the following:
• Reply to at least two different classmates outside of your own initial post thread.
• In Module One, complete the two response posts by Sunday at 11:59
p.m. Eastern Time.
• In Modules Two through Eight, complete the two response posts by Sunday at 11:59 p.m. of your local time zone.
• Demonstrate more depth and thought than simply stating that “I agree” or “You are wrong.” Guidance is provided for you in each discussion prompt. Discussion: Cellular Adaptation NUR 315 Discussion Cellular Adaptation
Rubric
Critical Elements Exemplary Proficient Needs Improvement Not Evident Value
Comprehension Develops an initial post with an organized, clear point of view or idea using rich and significant detail
(100%) Develops an initial post with a point of view or idea using adequate organization and
detail (85%) Develops an initial post with a point of view or idea but with some gaps in organization and
detail (55%) Does not develop an initial post with an organized point of view or idea (0%) 40
Timeliness Submits initial post on time (100%) Submits initial post one day late
(55%) Submits initial post two or more days late (0%) 10 Engagement Provides relevant and meaningful response posts with clarifying explanation and detail (100%) Provides relevant response posts with some explanation
and detail (85%) Provides somewhat relevant response posts with some  explanation and detail (55%) Provides response posts that are generic with little explanation or detail (0%) 30 Writing (Mechanics) Writes posts that are easily understood, clear, and concise using proper citation methods where applicable with no errors in
citations (100%) Writes posts that are easily understood using proper citation methods where applicable with few errors in citations (85%) Writes posts that are understandable using proper citation methods where applicable with a number of errors in citations (55%) Writes posts that others are not able to understand and does not use proper citation methods where applicable (0%) 20. Discussion: Cellular Adaptation Total 100% NUR 315 Discussion Cellular Adaptation

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